Honey has historically been used as a therapeutic agent, and this use dates back over many centuries. In more modern times, honey has seen a growing interest around its natural remedies, which has lead to numerous scientific investigations. Research in New Zealand has tried and proven that Mānuka honey possesses unique and special healing properties, and t has been dubbed by many “the best natural antibiotic in the world.” The studies have also concluded that Mānuka honey’s antibacterial properties are a result of more than just the sugars contained. Two major sources have been proven to contribute to this antimicrobial activity, hydrogen peroxide, which is produced by the bees, and uncharacterised chemical substances, which are gained from the floral source, Using honeys sources around Australia are screened against several reference microorganisms, the antimicrobial potency of a specific Australian honey was shown to be comparable to NZ Mānuka honey. Early chemical comparisons confirmed that New Zealand and Australian Mānuka honeys are very similar, which is not overly surprising due to the fact that they both originate from Leptospermum trees.